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Akorn Promethazine Syrup Oral Solution
Everything You Need to Know About Akorn Promethazine Syrup Oral Solution: The Ultimate Guide That Could Save Your Life
If you or a loved one has been prescribed Akorn Promethazine Syrup Oral Solution, you need clear, reliable information to use it safely and effectively. This guide covers everything—from what it treats and how it works, to dosage, side effects, and critical safety warnings that could save your life.biospace+1
What Is Akorn Promethazine Syrup Oral Solution?
Akorn Promethazine Syrup Oral Solution is a prescription medication containing promethazine hydrochloride, a powerful antihistamine (phenothiazine derivative). It’s used to relieve symptoms of allergies, colds, and other respiratory conditions.pharmacy.amazon+1
Akorn markets several formulations under its Hi-Tech Pharmacal label, including:
Promethazine/Phenylephrine Syrup – for nasal congestion and cold symptoms.
Promethazine/Phenylephrine/Codeine Syrup – for coughs and upper respiratory symptoms.biospace
The standard promethazine oral solution strength is 6.25 mg per 5 mL (1 teaspoon), often available in 16 oz (473 mL) bottles.medlineplus+2
What Does Akorn Promethazine Syrup Treat?
Promethazine works by blocking histamine, a substance released during allergic reactions. It’s commonly used for:pharmacy.amazon
Allergic rhinitis (runny nose, watery eyes from pollen, mold, or dust)
Allergic conjunctivitis (red, itchy eyes)
Allergic skin reactions
Cold symptoms (sneezing, cough, runny nose)
Nausea and vomiting (post-surgery or motion sickness)
Sedation before/after surgery or during laborpharmacy.amazon+1
When combined with phenylephrine or codeine, it also helps with nasal congestion and cough suppression.mayoclinic+2
How to Use Akorn Promethazine Syrup Safely
Dosage Guidelines
Adults and children 12+ years:
5 mL (1 teaspoon) every 4–6 hours as needed.
Do not exceed 30 mL (6 teaspoons) in 24 hours.dailymed.nlm.nih
Children 6–11 years:
2.5–5 mL (½–1 teaspoon) every 4–6 hours.
Do not exceed 30 mL in 24 hours.dailymed.nlm.nih
Children under 6 years:
Not recommended for syrup due to risk of respiratory depression.
Children under 2 years:
Contraindicated—promethazine should not be used at all.ncbi.nlm.nih
Always follow your prescriber’s instructions. Use a proper measuring device (not a kitchen spoon) to avoid overdose.
Side Effects and Warnings
Common Side Effects
Drowsiness (most prominent)
Dry mouth
Dizziness, blurred vision
Nausea, vomiting
Confusion, restlessness (especially in children)mayoclinic+2
Serious Side Effects (Seek Medical Help Immediately)
Slowed or stopped breathing
Severe drowsiness or inability to stay awake
Hallucinations, confusion, seizures
Yellowing of skin/eyes (liver problems)
Uncontrollable muscle movements, stiff muscles
Fast or irregular heartbeat
Signs of infection (fever, sore throat, chills)
Allergic reactions (swelling, rash, difficulty breathing)mayoclinic+1
Critical Safety Warnings
Do not mix with alcohol—this can cause dangerously slowed breathing.dailymed.nlm.nih
Avoid driving or operating machinery—promethazine causes significant sedation.webmd
Not for children under 2 years—risk of fatal respiratory depression.ncbi.nlm.nih
Use caution in elderly patients—higher risk of confusion, falls, and side effects.goodrx
Sun sensitivity—promethazine can make your skin more sensitive to sunlight.goodrx
Drug Interactions
Akorn Promethazine Syrup can interact with:
Other CNS depressants (alcohol, opioids, benzodiazepines, sleep aids) – increased sedation and breathing risk.mayoclinic
MAO inhibitors – can cause severe reactions.
Anticholinergic drugs – may worsen dry mouth, blurred vision, constipation.
Always tell your doctor about all medications you’re taking.
FAQs About Akorn Promethazine Syrup Oral Solution
1. What is Akorn Promethazine Syrup Oral Solution used for?
It treats allergy symptoms (runny nose, sneezing, itchy eyes), cold symptoms, nausea, and can provide sedation before/after medical procedures.pharmacy.amazon+1
2. How much Akorn Promethazine Syrup can I take in a day?
Adults and children 12+ should not exceed 30 mL (6 teaspoons) in 24 hours. Children 6–11 years should not exceed 30 mL either.dailymed.nlm.nih
3. Is Akorn Promethazine Syrup safe for children?
No for children under 2 years. Not recommended for children under 6 years for syrup due to respiratory depression risk. Always consult a pediatrician.ncbi.nlm.nih
4. Can I drink alcohol while taking this syrup?
No—alcohol can dangerously slow breathing and increase drowsiness when combined with promethazine.dailymed.nlm.nih
5. What are the most common side effects?
Drowsiness, dry mouth, dizziness, blurred vision, nausea, and confusion (especially in children).mayoclinic+1
6. Can Akorn Promethazine Syrup cause addiction?
Promethazine alone is not addictive, but formulations with codeine (an opioid) can be habit-forming if misused.mayoclinic
7. What should I do if I miss a dose?
Take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double up.
Final Thoughts: Stay Informed, Stay Safe
Akorn Promethazine Syrup Oral Solution can provide powerful relief for allergies, colds, and nausea—but it must be used responsibly. Knowing the right dosage, side effects, and safety warnings could save your life or the life of someone you love.
